有機(jī)合成百題精解

第一章 解答有機(jī)合成題的基礎(chǔ)知識(shí)準(zhǔn)備················································································ 1
一、烴類(lèi)和簡(jiǎn)單雜環(huán)的官能團(tuán)化····························································································· 1
二、官能團(tuán)的轉(zhuǎn)換················································································································ 6
三、復(fù)習(xí)和熟練掌握碳鏈的增長(zhǎng)方法······················································································ 9
四、熟悉一些重要的重排反應(yīng)······························································································ 10
五、掌握碳碳鍵的構(gòu)建方法·································································································· 10
六、掌握化學(xué)鍵的切斷與逆合成分析法················································································· 10
七、熟悉按照化學(xué)鍵異裂方式切斷后的常見(jiàn)合成子及其對(duì)應(yīng)的等價(jià)物······································· 10
八、逆合成分析切斷法的技巧······························································································ 11
九、一條理想的合成路線的確定需要把握的幾點(diǎn)···································································· 11
第二章 有機(jī)化合物常見(jiàn)增長(zhǎng)和縮短碳鏈的方法····································································· 12
第一節(jié) 增長(zhǎng)碳鏈的方法····································································································· 12
一、增加一個(gè)碳原子的常見(jiàn)方法··························································································· 12
二、增加兩個(gè)碳原子的常見(jiàn)方法··························································································· 16
三、增加三個(gè)碳原子的常見(jiàn)方法··························································································· 19
四、增加四個(gè)碳原子的常見(jiàn)方法··························································································· 22
五、碳鏈倍增法·················································································································· 22
第二節(jié) 縮短碳鏈的方法····································································································· 24
一、減少一個(gè)碳原子的常見(jiàn)方法··························································································· 24
二、烯烴通過(guò)氧化斷鍵減少一個(gè)或多個(gè)碳的方法···································································· 25
第三章 有機(jī)合成練習(xí)題題解······························································································· 26
參考文獻(xiàn)·························································································································· 238