Introduction to Skin Biothermomechanics and Thermal Pain introduces the study of coupled bio-thermo-mechanical and neural behavior of skin tissue in response to thermal and mechanical loads. The research in this book focuses on the theoretical modeling and experimental investigation of heated skin tissue in order to provide a predictive framework for thermal therapies of diseased tissue in clinics. Furthermore， by developing solution tools， it focuses on changes in treatment parameters leading to more effective therapies. The book is intended for researchers and scientists in Bioengineering，Heat Transfer， Mechanics， Biology and Neurophysiology， as well as clinicians.
作者簡介
Dr. Feng Xu is a research fellow at Harvard Medical School， Boston， MA，USA. Dr. Tianjian Lu is a professor at the School of Aerospace， Xi''an Jiaotong University， Xi''an， China. Dr. Xu and Dr. Lu are also affiliated with Biomedical Engineering and Biomechanics Center at Xi''an Jiaotong University， Xi''an， China.
圖書目錄
Chapter 1 Introduction 1.1 Introduction 1.2 Skin Biothermomechanics and Thermal Pain 1.3 Outline of the Book References Chapter 2 Skin Structure and Skin Blood Flow 2.1 Introduction 2.2 Skin Structure 2.3 Skin Blood Perfnsion References PART Ⅰ SKIN BIOHEAT TRANSFER Chapter 3 Skin Bioheat Transfer and Skin Thermal Damage 3.1 Introduction 3.2 Skin Bioheat Transfer 3.3 Skin Thermal Damage 3.4 Summary References Chapter 4 Analysis of Skin Bioheat Transfer 4.1 Introduction 4.2 Skin Bioheat Transfer Analysis with Fourier Model 4.3 Skin Bioheat Transfer Analysis with Non-Fourier Models 4.4 Summary References PART Ⅱ SKIN BIOMECHANICS Chapter 5 Skin Mechanical Behaviour 5.1 Introduction 5.2 Skin Behaviour under Stretch 5.3 Skin Behaviour under Compression 5.4 Skin Failure 5.5 Skin Friction References Chapter 6 Skin Biomechanics Experiments: Measurement and Influence of Different Factors 6.1 Introduction 6.2 In Vivo Measurements 6.3 In Vitro Measurements 6.4 Influence of Different Factors 6.5 Summary References Chapter 7 Skin Biomechanics Modeling 7.1 Introduction 7.2 Continuum Models and Phenomenological Models 7.3 Structural Models 7.4 Summary References PART Ⅲ SKIN BIOTHERMOMECHANICS Chapter 8 Introduction of Skin Biothermomechanics 8.1 Introduction 8.2 Mechanism of Thermal Denaturation (Shrinkage) of Collagen 8.3 Properties Variations due to Thermal Denaturation of Collagen References Chapter 9 Analysis of Skin Biothermomechanics 9.1 Introduction 9.2 Theoretical Analysis of Thermal Stress 9.3 Analysis with Fourier Bioheat Transfer Models 9.4 Analysis with Non-Fourier Bioheat Transfer Models 9.5 Summary 9.6 Appendix References Chapter 10 Experimental Characterization of Skin Biothermomechanics 10.1 Introduction 10.2 Experimental Methodology 10.3 Thermal Denaturation of Collagen in Skin Tissue 10.4 Hydrothermal Tensile Tests 10.5 Hydrothermal Compressive Tests 10.6 Characterization of Skin Viscoelasticity with Static Tests 10.7 Summary and Limitations References PART Ⅳ SKIN THERMAL PAIN Chapter 11 Skin Thermal Pain Mechanism 11.1 Introduction 11.2 Definition of Pain and Pain Pathways 11.3 Anatomy and Physiology of Nociceptors 11.4 Theories of Thermal Pain References Chapter 12 Physiological Features of Pain Sensation 12.1 Introduction 12.2 Role of C and Aδ Nociceptors 12.3 Influence of Stimulus Temperature on Pain 12.4 Influence of Nociceptors Depth 12.5 Influence of Temperature Change Rate on Pain 12.6 Temporal Summation 12.7 Influence of Stimulus Duration 12.8 Spatial Summation 12.9 Hyperalgesia and Tissue Damage 12.10 Influence of Origin of Skin (Different Part in Body) 12.11 Influence of Skin Type 12.12 Gender Difference 12.13 Influence of Age 12.14 Summary References Chapter 13 Skin Thermal Pain Modeling 13.1 Introduction 13.2 Model of Transduction 13.3 Model of Transmission 13.4 Model of Modulation and Perception 13.5 Results and Discussion 13.6 Summary References
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